Clinical Curative Effect on the Leep Combined with Basic Fibroblast Growth Factor in the Treatment of Cervical Ectopic Columnar Epithelium
Objective : To investigate clinical efficacy and safety of the loop electrosurgical excision procedure (LEEP) combined with basic fibroblast growth factor (bFGF) in the treatment of cervical ectopic columnar epithelium.
Methods : Sixty patients with III degree cervical ectopic columnar epithelium randomly divided into observation group and control group with 30 cases in each group,were treated with LEEP therapy. The observation group was given topical bFGF treatment on 7 d, 14 d and 21 d after operation．
Results : On 14 d and 21 d after operation, the wound healing area in observation group was larger than that in the control group (P＜0.05), postoperative vaginal discharge time and wound healing time of the observation group was shorter than that of the control group (P＜0.01), the effective rate of the treatment group was 93.33%, higher than 73.33% of the control group (P＜0.05). No serious complications such as postoperative bleeding and cervical adhesions occurred in the two groups．
Conclusion : LEEP combined with bFGF in the treatment of ectopic cervical columnar epithelium can promote wound healing, shorten the wound healing time and reduce postoperative vaginal discharge.
Observation of Curative Effect of Leep Surgery Combined with Growth Factors in the Treatment of 720 Patients with Chronic Cervicitis
Objective : To discuss the curative effect of growth factors in wound recovery after LEEP surgery in patients with chronic cervicitis.
Methods : LEEP surgeries were adopted in 720 cases of patients with cervical erosion. All patients were divided into experiment group and control group after surgery, 360 cases in each group. Basic fibroblast growth factor and Metronidazole powder were used in surgical wounds in experiment group,and only Metronidazole powder were used in control group. The postoperative conditions were observed and recorded after surgery.
Results : The cure rate was 99.7% in experiment group and 88.89% in control group; the time of postoperative liquid flow was (9.0±2.5) d in experiment group and (15.0±2.2) d in control group; 23 cases had postoperative bleeding in experiment group with the ratio of 6.38%, 61 cases had postoperative bleeding in control group with the ratio of 16.94%. Compared with control group,the above experimental indicators were significantly differences in experiment group (P<0.05).
Conclusion : LEEP surgery combined with the use of growth factors can effectively improve the cure rate, shorten the time of postoperative liquid flow, reduce the incidence of postoperative wound bleeding and easily use.
The Influence of Basic Fibroblast Growth Factor on Post Cervical LEEP Wound Healing for Chronic Cervicitis
Objective : To observe the influence and safety of external use of basic fibroblast growth factor (bFGF), after cervical loop electrosurgical excision procedure (LEEP) for chronic cervicitis.
Methods : Classify 100 post LEEP patients into observance group (routine oral administration of antibiotics to prevent infection + bFGF) and control group (routine oral administration of antibiotics to prevent infection), and observe wound healing and healing time, vaginal discharge, bleeding amount and duration.
Results : The wound healing time of observance group is remarkably shortened, vaginal discharge amount is greatly reduced, and duration is shortened.
Conclusion : Basic fibroblast growth factor can obviously promote post LEEP cervical wound healing for chronic cervicitis.