Observation on the Curative Effect of BFGF in Reducing Wound Pain and Inhibiting the Proliferation of Residual Traces
Objective : To explore the effect of bFGF on reducing wound pain and inhibiting scar hyperplasia.
Methods : 164 cases of cholecystectomy patients were treated with bFGF (treatment group) and 93 cases without bFGF (control group). The two main indicators of pain and scar were observed.
Results : The wound healing time was (6.13±1.09) days in the treatment group and (7.24±1.22) days in the control group (P<0.05). The quality of wound healing in the treatment group was 93.0% for grade A, 5.9% for grade B, 1.1% for grade C, and 85.0% for grade A, 10.8% for grade B, and 4.2% for grade C in the control group. The incidence of scarring in the treatment group was lower than that in the control group.
Conclusion : bFGF can shorten wound healing time, reduce wound pain, and improve wound healing quality.
34 Cases of Fractional Er: Yag Laser Combined with BFGF in the Treatment of Facial Atrophic Acne Scar
Objective : To observe the effect and safety of bFGF auxiliary fractional Er: YAG laser in the treatment of facial atrophic acne scar.
Methods : After fractional Er: YAG laser treatment, 64 cases of facial atrophic acne scar patients were randomly divided into two groups. The observation group was applied facial ice collagen dressing and sprayed fibroblast growth factor; the control group was only applied facial ice collagen dressing.Treatment in two groups last for 10 consecutive days. Postoperative to observe the wound healing time, adverse reactions, using B. Dreno's ECCA grading scale to identify and quantify facial atrophic scars before and after treatment and conduct statistics of the satisfactory rate of patients.
Results : The wounds of two groups were conventional healing, the average healing time in the observation group was 7.2 days, and that of control group was 10.4 days, there was significant difference (P<0.05). For all patients at the end of treatment and followed-up 3months later, scar were all improved, with an efficiency of 100%.
Conclusion : Fractional Er: YAG laser combined with bFGF is a safe and effective treatment method for treatment of facial atrophic acne scars.